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Chronic Myeloid Leukemia is a type of cancer that starts in certain blood-forming cells of the bone marrow. Interferon-\(\alpha\) was once the standard front-line treatment producing remission rates of only 28.3 percent in 1991. After the highly effective drugs first became available in 2001, survival rates have increased immensely. According to the American Cancer Society, one large study of CML patients treated with a drug called imatinib found that about 90 percent of them were still alive 5 years after starting treatment. While imatinib has changed the way oncologists treat CML, remission is common after extended gaps in treatment. In this paper, we will explore the long-term dynamics of CML under treatment through the use of use of theoretical and mathematical components. We closely base our methods upon the approach of Urszula Ledzewicz and Helen Moore. We will introduce our unique model and explain component selections, while we move towards understanding the optimal interactions of imatinib and interferon-\(\alpha\) against dormant and proliferating CML cells. Our future work involving optimal control dynamics will be briefly introduced and further solutions are currently ongoing.

We present a geometric proof of the addition formulas for the hyperbolic sine and cosine functions, using elementary properties of linear transformations.

This template is for authors who are preparing a manuscript for IISE Transactions using the LaTeX document preparation system. Please check “Instructions for authors” on IISE Transactions’ website for additional information.

Trabalho de Física Experimental II

This is the paper template for the Euroregio Baltic Nordic Acoustic Meeting 2022, to be held in Aalborg, Denmark from 9th-11th of May 2022. The template uses the XeLaTeX compiler.

Trabalho de Introdução à Sociologia - Engenharia da Computação - CEFET/MG

山中 卓 (大阪大学 大学院理学研究科 物理学専攻)先生が作成された科研費LaTeXを、坂東 慶太 (名古屋学院大学) が了承を得てテンプレート登録しています。 詳細はこちら↓をご確認ください。 http://osksn2.hep.sci.osaka-u.ac.jp/~taku/kakenhiLaTeX/

Ce template est destiné à l'ensemble du réseau Polytech. Il permet de créer un document comme un rapport, compte-rendu... Il est adapté à chaque école (tous les logos sont disponibles). De plus, un logo de l'université Paris-Saclay y est disoponible.
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